ACTIVATION OF THE NRF2/KEAP1 SIGNALING PATHWAY MEDIATES THE NEUROPROTECTIVE EFFECT OF PERILLYL ALCOHOL AGAINST CEREBRAL HYPOXIC-ISCHEMIC DAMAGE IN NEONATAL RATS

Neonatal hypoxic-ischemic encephalopathy (HIE) is a severe disease with a poor prognosis, whose clinical treatment is still limited to therapeutic hypothermia with limited efficacy.Perillyl alcohol (POH), a natural monoterpene found in various plant essential oils, has shown neuroprotective properties, though its effects on HIE are not well underst

BackgroundSuicide is the second leading cause of death among young people worldwide FRESH MINT FOAMING HAND SOAP and remains a major public health concern.Research indicates that negative social contexts involving familial and peer relationships, have far-reaching influences on levels of suicidal behaviours in later life.Previous systematic reviews

Penulisan artikel ini bertujuan untuk menyelesaikan permasalahan Vehicle Routing Problem with Time Windows (VRPTW) dengan menggunakan Hybrid Crow Search Algorithm (CSA) dengan Simulated Annealing (SA).Hybrid CSA dengan SA adalah gabungan dari kedua algoritma dengan cara melakukan proses CSA kemudian hasil terburuknya diperbaiki Freewheel Pulley den